Effect of Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain on hepatotoxicity induced by rifampicin in rats just after rainy season [August-September]

To assess the hepatoprotective activity of Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain frothless juice of Mako [Solanum nigrum] leaves, and Kasni [Cichorium intybus] leaves and collectively leaves of both plants on Rifampicin-induced hepatotoxicity in Wistar albino rats. Hepatotoxicity was induced in rats by Rifampicin given orally as suspension for 30 days. Concurrent group received Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain alongwith Rifampicin. In the second phase of study the effect of Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain on established hepatotoxicity was studied by giving the Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain for 20 days after withdrawal of Rifampicin. Hepatic dysfunction was assessed by biochemical and histological parameters. Muravvaq of Mako, Muravvaq of Kasni and Muravvaqain significantly [p<0.05] prevented changes in the serum levels of bilirubin, SGOT, SGPT and SALP. Similarly it significantly prevented the histological changes as compared to the group receiving Rifampicin. It also significantly reversed the biochemical and histological changes

Effect of supari chikni [areca catechu], mochras [salmah malabarica], chhal molsari [mimusops elen.], barg-e-kasni [cichorium intybus] and gul-e-dhawa [woodfordia floribunda] on sailan-ur-reham taffuni [infected vaginal discharge] a clinical study

According to Unani System of Medicine, Sailan-ur-Reham [vaginal discharge] means a discharge which passes through the vagina, it may be blood stained or otherwise. The vaginal discharge can be of physiological or pathological type. Pathological discharge is further divided into leucorrhoea and inflammatory discharge [due to infections of vagina-cervix-uterus]. In our study cases of Sailan-ur-Reham Zltihabi [due to certain specific infections] were put on a compound formulation [in form of vaginal tablet of 1 gm] for clinical trial on single blind technique. Vaginal pessary was given to patients for vaginal insertion daily at night for about two weeks. The study was carried out in 45 patients aged 21-50 yrs. Patients were divided into two groups. The control group was treated with placebo. The test group was treated with the test drug in form of vaginal tablet for fifteen days at bedtime, the outcome was assessed by symptoms, clinical examination and investigation. The drug combination produced significant improvement in the disease